PDB Information

PDB6MJU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Lama, L., Adura, C., Xie, W., Tomita, D., Kamei, T., Kuryavyi, V., Gogakos, T., Steinberg, J.I., Miller, M., Ramos-Espiritu, L., Asano, Y., Hashizume, S., Aida, J., Imaeda, T., Okamoto, R., Jennings, A.J., Michino, M., Kuroita, T., Stamford, A., Gao, P., Meinke, P., Glickman, J.F., Patel, D.J., Tuschl, T.
Nat Commun
HeaderTransferase/Transferase Inhibitor
Released2018-09-22
Resolution2.450
CATH Insert Date02 Jun, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Jun, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6mjuA01 03 Jun, 2019 1.10.1410.40 Assigned
6mjuA02 03 Jun, 2019 3.30.460.90 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8N884 CGAS_HUMAN Homo sapiens Cyclic GMP-AMP synthase
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