PDB Information

PDB6IOL
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli
Gene SourcePseudomonas aeruginosa
Primary Citation
Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Tsutsumi, K., Yonehara, R., Ishizaka-Ikeda, E., Miyazaki, N., Maeda, S., Iwasaki, K., Nakagawa, A., Yamashita, E.
Nat Commun
HeaderMembrane Protein
Released2018-10-30
Resolution3.760
CATH Insert Date07 Apr, 2019

PDB Images (19)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped
C 07 Apr, 2019 Chopped
E 07 Apr, 2019 Holding pen
F 07 Apr, 2019 Holding pen
G 07 Apr, 2019 Holding pen
I 07 Apr, 2019 Holding pen
J 07 Apr, 2019 Holding pen
K 07 Apr, 2019 Holding pen
L 07 Apr, 2019 Holding pen
M 07 Apr, 2019 Holding pen
N 07 Apr, 2019 Holding pen

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6iolA01 08 Apr, 2019 1.20.1600.10 Assigned
6iolA02 08 Apr, 2019 2.20.200.10 Assigned
6iolB01 08 Apr, 2019 1.20.1600.10 Assigned
6iolB02 08 Apr, 2019 2.20.200.10 Assigned
6iolC01 08 Apr, 2019 1.20.1600.10 Assigned
6iolC02 08 Apr, 2019 2.20.200.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA