PDB 6ijh
PDB Information
PDB | 6IJH |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli BL21 |
Gene Source | Homo sapiens |
Primary Citation | Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
J. Med. Chem.
|
Header | Hydrolase/Inhibitor |
Released | 2018-10-10 |
Resolution | 2.600 |
CATH Insert Date | 14 Apr, 2019 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 14 Apr, 2019 | Chopped |
B | 14 Apr, 2019 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
6ijhA00 | 15 Apr, 2019 | 1.10.1300.10 | Assigned |
6ijhB00 | 15 Apr, 2019 | 1.10.1300.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q9Y233 | PDE10_HUMAN | Homo sapiens | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
Q9Y233 | PDE10_HUMAN | Homo sapiens | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |