PDB 6i8s

PDB Information

PDB6I8S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Vousden, K.A., Lundqvist, T., Popovic, B., Naiman, B., Carruthers, A.M., Newton, P., Johnson, D.J.D., Pomowski, A., Wilkinson, T., Dufner, P., de Mendez, I., Mallinder, P.R., Murray, C., Strain, M., Connor, J., Murray, L.A., Sleeman, M.A., Lowe, D.C., Huntington, J.A., Vaughan, T.J.
Sci Rep
HeaderBlood Clotting
Released2018-11-21
Resolution2.900
CATH Insert Date17 Feb, 2019

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 17 Feb, 2019 Chopped
B 17 Feb, 2019 Chopped
C 17 Feb, 2019 Chopped
D 17 Feb, 2019 Chopped
E 17 Feb, 2019 Holding pen
F 17 Feb, 2019 Holding pen
G 17 Feb, 2019 Holding pen
H 17 Feb, 2019 Holding pen
I 17 Feb, 2019 Chopped
J 17 Feb, 2019 Chopped
K 17 Feb, 2019 Chopped
L 17 Feb, 2019 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6i8sA01 18 Feb, 2019 3.30.497.10 Assigned
6i8sA02 18 Feb, 2019 2.30.39.10 Assigned
6i8sB01 18 Feb, 2019 3.30.497.10 Assigned
6i8sB02 18 Feb, 2019 2.30.39.10 Assigned
6i8sC01 18 Feb, 2019 3.30.497.10 Assigned
6i8sC02 18 Feb, 2019 2.30.39.10 Assigned
6i8sD01 18 Feb, 2019 3.30.497.10 Assigned
6i8sD02 18 Feb, 2019 2.30.39.10 Assigned
6i8sI01 18 Feb, 2019 2.60.40.10 Assigned
6i8sI02 18 Feb, 2019 2.60.40.10 Assigned
6i8sJ01 18 Feb, 2019 2.60.40.10 Assigned
6i8sJ02 18 Feb, 2019 2.60.40.10 Assigned
6i8sK01 18 Feb, 2019 2.60.40.10 Assigned
6i8sK02 18 Feb, 2019 2.60.40.10 Assigned
6i8sL01 18 Feb, 2019 2.60.40.10 Assigned
6i8sL02 18 Feb, 2019 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P05121 PAI1_HUMAN Homo sapiens Plasminogen activator inhibitor 1
P05121 PAI1_HUMAN Homo sapiens Plasminogen activator inhibitor 1
P05121 PAI1_HUMAN Homo sapiens Plasminogen activator inhibitor 1
P05121 PAI1_HUMAN Homo sapiens Plasminogen activator inhibitor 1