PDB 6i3s

PDB Information

PDB6I3S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Targeted Synthesis of Complex Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2-p53 Inhibitors.
Gollner, A., Weinstabl, H., Fuchs, J.E., Rudolph, D., Garavel, G., Hofbauer, K.S., Karolyi-Oezguer, J., Gmaschitz, G., Hela, W., Kerres, N., Grondal, E., Werni, P., Ramharter, J., Broeker, J., McConnell, D.B.
ChemMedChem
HeaderLigase
Released2018-11-07
Resolution1.770
CATH Insert Date23 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6i3sA00 27 Dec, 2018 1.10.245.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
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