PDB 6i12

PDB Information

PDB6I12
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Francis, S., Croft, D., Schuttelkopf, A.W., Parry, C., Pugliese, A., Cameron, K., Claydon, S., Drysdale, M., Gardner, C., Gohlke, A., Goodwin, G., Gray, C.H., Konczal, J., McDonald, L., Mezna, M., Pannifer, A., Paul, N.R., Machesky, L., McKinnon, H., Bower, J.
Bioorg.Med.Chem.Lett.
HeaderStructural Protein
Released2018-10-27
Resolution1.650
CATH Insert Date03 Mar, 2019

PDB Images (6)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6i12A01 04 Mar, 2019 2.80.10.50 Assigned
6i12A02 04 Mar, 2019 2.80.10.50 Assigned
6i12A03 04 Mar, 2019 2.80.10.50 Assigned
6i12A04 04 Mar, 2019 2.80.10.50 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16658 FSCN1_HUMAN Homo sapiens Fascin