PDB 6i07

PDB Information

PDB6I07
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Casaletto, J.B., Geddie, M.L., Abu-Yousif, A.O., Masson, K., Fulgham, A., Boudot, A., Maiwald, T., Kearns, J.D., Kohli, N., Su, S., Razlog, M., Raue, A., Kalra, A., Hakansson, M., Logan, D.T., Welin, M., Chattopadhyay, S., Harms, B.D., Nielsen, U.B., Schoeberl, B., Lugovskoy, A.A., MacBeath, G.
Proc.Natl.Acad.Sci.USA
HeaderImmune System
Released2018-10-25
Resolution2.350
CATH Insert Date17 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Holding pen
B 17 Mar, 2019 Holding pen
C 17 Mar, 2019 Holding pen
D 17 Mar, 2019 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P16422 EPCAM_HUMAN Homo sapiens Epithelial cell adhesion molecule
P16422 EPCAM_HUMAN Homo sapiens Epithelial cell adhesion molecule