PDB Information

PDB6HV0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1 alpha Kinase-Endoribonuclease.
Colombano, G., Caldwell, J.J., Matthews, T.P., Bhatia, C., Joshi, A., McHardy, T., Mok, N.Y., Newbatt, Y., Pickard, L., Strover, J., Hedayat, S., Walton, M.I., Myers, S.M., Jones, A.M., Saville, H., McAndrew, C., Burke, R., Eccles, S.A., Davies, F.E., Bayliss, R., Collins, I.
J.Med.Chem.
HeaderSignaling Protein
Released2018-10-09
Resolution2.730
CATH Insert Date03 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
6hv0A01 04 Mar, 2019 3.30.200.20 Assigned
6hv0A02 04 Mar, 2019 1.10.510.10 Assigned
6hv0A03 04 Mar, 2019 1.20.1440.180 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1