PDB 6htd

PDB Links
Overview

PDB Information

PDB	6HTD
Method	X-RAY DIFFRACTION
Host Organism	Saccharomyces cerevisiae S288c
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. Xin, B.T., Huber, E.M., de Bruin, G., Heinemeyer, W., Maurits, E., Espinal, C., Du, Y., Janssens, M., Weyburne, E.S., Kisselev, A.F., Florea, B.I., Driessen, C., van der Marel, G.A., Groll, M., Overkleeft, H.S. J.Med.Chem.
Header	Hydrolase
Released	2018-10-03
Resolution	3.000
CATH Insert Date	03 Feb, 2019

PDB Images (57)

6htd

PDB 6htd

6htda

PDB Chain 6htda

6htdA

PDB Chain 6htdA

6htdb

PDB Chain 6htdb

6htdB

PDB Chain 6htdB

6htdC

PDB Chain 6htdC

6htdD

PDB Chain 6htdD

6htdE

PDB Chain 6htdE

6htdF

PDB Chain 6htdF

6htdG

PDB Chain 6htdG

6htdH

PDB Chain 6htdH

6htdI

PDB Chain 6htdI

6htdJ

PDB Chain 6htdJ

6htdK

PDB Chain 6htdK

6htdL

PDB Chain 6htdL

6htdM

PDB Chain 6htdM

6htdN

PDB Chain 6htdN

6htdO

PDB Chain 6htdO

6htdP

PDB Chain 6htdP

6htdQ

PDB Chain 6htdQ

6htdR

PDB Chain 6htdR

6htdS

PDB Chain 6htdS

6htdT

PDB Chain 6htdT

6htdU

PDB Chain 6htdU

6htdV

PDB Chain 6htdV

6htdW

PDB Chain 6htdW

6htdX

PDB Chain 6htdX

6htdY

PDB Chain 6htdY

6htdZ

PDB Chain 6htdZ

6htda00

CATH Domain 6htda00

6htdA00

CATH Domain 6htdA00

6htdb00

CATH Domain 6htdb00

6htdB00

CATH Domain 6htdB00

6htdC00

CATH Domain 6htdC00

6htdD00

CATH Domain 6htdD00

6htdE00

CATH Domain 6htdE00

6htdF00

CATH Domain 6htdF00

6htdG00

CATH Domain 6htdG00

6htdH00

CATH Domain 6htdH00

6htdI00

CATH Domain 6htdI00

6htdJ00

CATH Domain 6htdJ00

6htdK00

CATH Domain 6htdK00

6htdL00

CATH Domain 6htdL00

6htdM00

CATH Domain 6htdM00

6htdN00

CATH Domain 6htdN00

6htdO00

CATH Domain 6htdO00

6htdP00

CATH Domain 6htdP00

6htdQ00

CATH Domain 6htdQ00

6htdR00

CATH Domain 6htdR00

6htdS00

CATH Domain 6htdS00

6htdT00

CATH Domain 6htdT00

6htdU00

CATH Domain 6htdU00

6htdV00

CATH Domain 6htdV00

6htdW00

CATH Domain 6htdW00

6htdX00

CATH Domain 6htdX00

6htdY00

CATH Domain 6htdY00

6htdZ00

CATH Domain 6htdZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	03 Feb, 2019	Chopped
A	03 Feb, 2019	Chopped
b	03 Feb, 2019	Chopped
B	03 Feb, 2019	Chopped
C	03 Feb, 2019	Chopped
D	03 Feb, 2019	Chopped
E	03 Feb, 2019	Chopped
F	03 Feb, 2019	Chopped
G	03 Feb, 2019	Chopped
H	03 Feb, 2019	Chopped
I	03 Feb, 2019	Chopped
J	03 Feb, 2019	Chopped
K	03 Feb, 2019	Chopped
L	03 Feb, 2019	Chopped
M	03 Feb, 2019	Chopped
N	03 Feb, 2019	Chopped
O	03 Feb, 2019	Chopped
P	03 Feb, 2019	Chopped
Q	03 Feb, 2019	Chopped
R	03 Feb, 2019	Chopped
S	03 Feb, 2019	Chopped
T	03 Feb, 2019	Chopped
U	03 Feb, 2019	Chopped
V	03 Feb, 2019	Chopped
W	03 Feb, 2019	Chopped
X	03 Feb, 2019	Chopped
Y	03 Feb, 2019	Chopped
Z	03 Feb, 2019	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6htda00	04 Feb, 2019	3.60.20.10	Assigned
6htdA00	04 Feb, 2019	3.60.20.10	Assigned
6htdb00	04 Feb, 2019	3.60.20.10	Assigned
6htdB00	04 Feb, 2019	3.60.20.10	Assigned
6htdC00	04 Feb, 2019	3.60.20.10	Assigned
6htdD00	04 Feb, 2019	3.60.20.10	Assigned
6htdE00	04 Feb, 2019	3.60.20.10	Assigned
6htdF00	04 Feb, 2019	3.60.20.10	Assigned
6htdG00	04 Feb, 2019	3.60.20.10	Assigned
6htdH00	04 Feb, 2019	3.60.20.10	Assigned
6htdI00	04 Feb, 2019	3.60.20.10	Assigned
6htdJ00	04 Feb, 2019	3.60.20.10	Assigned
6htdK00	04 Feb, 2019	3.60.20.10	Assigned
6htdL00	04 Feb, 2019	3.60.20.10	Assigned
6htdM00	04 Feb, 2019	3.60.20.10	Assigned
6htdN00	04 Feb, 2019	3.60.20.10	Assigned
6htdO00	04 Feb, 2019	3.60.20.10	Assigned
6htdP00	04 Feb, 2019	3.60.20.10	Assigned
6htdQ00	04 Feb, 2019	3.60.20.10	Assigned
6htdR00	04 Feb, 2019	3.60.20.10	Assigned
6htdS00	04 Feb, 2019	3.60.20.10	Assigned
6htdT00	04 Feb, 2019	3.60.20.10	Assigned
6htdU00	04 Feb, 2019	3.60.20.10	Assigned
6htdV00	04 Feb, 2019	3.60.20.10	Assigned
6htdW00	04 Feb, 2019	3.60.20.10	Assigned
6htdX00	04 Feb, 2019	3.60.20.10	Assigned
6htdY00	04 Feb, 2019	3.60.20.10	Assigned
6htdZ00	04 Feb, 2019	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4