PDB 6hrt
PDB Information
| PDB | 6HRT |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Homo sapiens |
| Primary Citation | A potent seven-membered cyclic BTK (Bruton's tyrosine Kinase) chiral inhibitor conceived by structure-based drug design to lock its bioactive conformation.
Bioorg.Med.Chem.Lett.
|
| Header | Transferase |
| Released | 2018-09-28 |
| Resolution | 1.360 |
| CATH Insert Date | 24 Mar, 2019 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 24 Mar, 2019 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6hrtA01 | 25 Mar, 2019 | 3.30.200.20 | Assigned |
| 6hrtA02 | 25 Mar, 2019 | 1.10.510.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q06187 | BTK_HUMAN | Homo sapiens | Tyrosine-protein kinase BTK |
