PDB 6hrp
PDB Information
PDB | 6HRP |
Method | X-RAY DIFFRACTION |
Host Organism | Spodoptera frugiperda |
Gene Source | Homo sapiens |
Primary Citation | A potent seven-membered cyclic BTK (Bruton's tyrosine Kinase) chiral inhibitor conceived by structure-based drug design to lock its bioactive conformation.
Bioorg.Med.Chem.Lett.
|
Header | Transferase |
Released | 2018-09-28 |
Resolution | 1.120 |
CATH Insert Date | 24 Mar, 2019 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 24 Mar, 2019 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
6hrpA01 | 25 Mar, 2019 | 3.30.200.20 | Assigned |
6hrpA02 | 25 Mar, 2019 | 1.10.510.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q06187 | BTK_HUMAN | Homo sapiens | Tyrosine-protein kinase BTK |