PDB Information

PDB6HMX
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
Haile, P.A., Casillas, L.N., Bury, M.J., Mehlmann, J.F., Singhaus Jr., R., Charnley, A.K., Hughes, T.V., DeMartino, M.P., Wang, G.Z., Romano, J.J., Dong, X., Plotnikov, N.V., Lakdawala, A.S., Convery, M.A., Votta, B.J., Lipshutz, D.B., Desai, B.M., Swift, B., Capriotti, C.A., Berger, S.B., Mahajan, M.K., Reilly, M.A., Rivera, E.J., Sun, H.H., Nagilla, R., LePage, C., Ouellette, M.T., Totoritis, R.D., Donovan, B.T., Brown, B.S., Chaudhary, K.W., Gough, P.J., Bertin, J., Marquis, R.W.
ACS Med Chem Lett
HeaderTransferase
Released2018-09-13
Resolution2.530
CATH Insert Date16 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6hmxA00 28 Feb, 2019 1.10.510.10 Assigned
6hmxB00 28 Feb, 2019 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O43353 RIPK2_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 2
O43353 RIPK2_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 2
CATH-Gene3D is a Global Biodata Core Resource Learn more...