PDB Information

PDB6HHF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib inKRAS-Mutant Pancreatic and Colorectal Cancer.
Weisner, J., Landel, I., Reintjes, C., Uhlenbrock, N., Trajkovic-Arsic, M., Dienstbier, N., Hardick, J., Ladigan, S., Lindemann, M., Smith, S., Quambusch, L., Scheinpflug, R., Depta, L., Gontla, R., Unger, A., Muller, H., Baumann, M., Schultz-Fademrecht, C., Gunther, G., Maghnouj, A., Muller, M.P., Pohl, M., Teschendorf, C., Wolters, H., Viebahn, R., Tannapfel, A., Uhl, W., Hengstler, J.G., Hahn, S.A., Siveke, J.T., Rauh, D.
Cancer Res.
HeaderTransferase
Released2018-08-28
Resolution2.900
CATH Insert Date24 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2019 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
6hhfA01 25 Mar, 2019 2.30.29.30 Assigned
6hhfA02 25 Mar, 2019 3.30.200.20 Assigned
6hhfA03 25 Mar, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P31749 AKT1_HUMAN Homo sapiens RAC-alpha serine/threonine-protein kinase
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