PDB 6gwr

PDB Links
Overview

PDB Information

PDB	6GWR
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. Wang, Z., Zhang, Y., Pinkas, D.M., Fox, A.E., Luo, J., Huang, H., Cui, S., Xiang, Q., Xu, T., Xun, Q., Zhu, D., Tu, Z., Ren, X., Brekken, R.A., Bullock, A.N., Liang, G., Ding, K., Lu, X. J. Med. Chem.
Header	Transferase
Released	2018-06-25
Resolution	2.070
CATH Insert Date	12 Aug, 2018

PDB Images (7)

Image of CATH 6gwr

6gwr

PDB 6gwr

Image of CATH 6gwrA

6gwrA

PDB Chain 6gwrA

Image of CATH 6gwrB

6gwrB

PDB Chain 6gwrB

Image of CATH 6gwrA01

6gwrA01

CATH Domain 6gwrA01

Image of CATH 6gwrA02

6gwrA02

CATH Domain 6gwrA02

Image of CATH 6gwrB01

6gwrB01

CATH Domain 6gwrB01

Image of CATH 6gwrB02

6gwrB02

CATH Domain 6gwrB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	12 Aug, 2018	Chopped
B	12 Aug, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6gwrA01	13 Aug, 2018	3.30.200.20	Assigned
6gwrA02	13 Aug, 2018	1.10.510.10	Assigned
6gwrB01	13 Aug, 2018	3.30.200.20	Assigned
6gwrB02	13 Aug, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q08345	DDR1_HUMAN	Homo sapiens	Epithelial discoidin domain-containing receptor 1
Q08345	DDR1_HUMAN	Homo sapiens	Epithelial discoidin domain-containing receptor 1