PDB Information

PDB6GMN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
Lucas, X., Van Molle, I., Ciulli, A.
J. Med. Chem.
HeaderOncoprotein
Released2018-05-27
Resolution1.940
CATH Insert Date12 Aug, 2018

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 12 Aug, 2018 Chopped
B 12 Aug, 2018 Chopped
C 12 Aug, 2018 Chopped
D 12 Aug, 2018 Chopped
E 12 Aug, 2018 Chopped
F 12 Aug, 2018 Chopped
G 12 Aug, 2018 Chopped
H 12 Aug, 2018 Chopped
I 12 Aug, 2018 Chopped
J 12 Aug, 2018 Chopped
K 12 Aug, 2018 Chopped
L 12 Aug, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6gmnA00 13 Aug, 2018 3.10.20.90 Assigned
6gmnB00 13 Aug, 2018 3.30.710.10 Assigned
6gmnC01 13 Aug, 2018 2.60.40.780 Assigned
6gmnC02 13 Aug, 2018 1.10.750.10 Assigned
6gmnD00 13 Aug, 2018 3.10.20.90 Assigned
6gmnE00 13 Aug, 2018 3.30.710.10 Assigned
6gmnF01 13 Aug, 2018 2.60.40.780 Assigned
6gmnF02 13 Aug, 2018 1.10.750.10 Assigned
6gmnG00 13 Aug, 2018 3.10.20.90 Assigned
6gmnH00 13 Aug, 2018 3.30.710.10 Assigned
6gmnI01 13 Aug, 2018 2.60.40.780 Assigned
6gmnI02 13 Aug, 2018 1.10.750.10 Assigned
6gmnJ00 13 Aug, 2018 3.10.20.90 Assigned
6gmnK00 13 Aug, 2018 3.30.710.10 Assigned
6gmnL01 13 Aug, 2018 2.60.40.780 Assigned
6gmnL02 13 Aug, 2018 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
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