PDB Information

PDB6GD4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceTrypanosoma brucei brucei
Primary Citation
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
Linciano, P., Pozzi, C., Iacono, L.D., di Pisa, F., Landi, G., Bonucci, A., Gul, S., Kuzikov, M., Ellinger, B., Witt, G., Santarem, N., Baptista, C., Franco, C., Moraes, C.B., Muller, W., Wittig, U., Luciani, R., Sesenna, A., Quotadamo, A., Ferrari, S., Pohner, I., Cordeiro-da-Silva, A., Mangani, S., Costantino, L., Costi, M.P.
J.Med.Chem.
HeaderOxidoreductase
Released2018-04-21
Resolution1.420
CATH Insert Date07 Apr, 2019

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped
C 07 Apr, 2019 Chopped
D 07 Apr, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6gd4A00 08 Apr, 2019 3.40.50.720 Assigned
6gd4B00 08 Apr, 2019 3.40.50.720 Assigned
6gd4C00 08 Apr, 2019 3.40.50.720 Assigned
6gd4D00 08 Apr, 2019 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
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