PDB 6fyz

PDB Links
Overview

PDB Information

PDB	6FYZ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor. Luckhurst, C.A., Aziz, O., Beaumont, V., Burli, R.W., Breccia, P., Maillard, M.C., Haughan, A.F., Lamers, M., Leonard, P., Matthews, K.L., Raphy, G., Stott, A.J., Munoz-Sanjuan, I., Thomas, B., Wall, M., Wishart, G., Yates, D., Dominguez, C. Bioorg. Med. Chem. Lett.
Header	Hydrolase
Released	2018-03-13
Resolution	2.150
CATH Insert Date	16 Dec, 2018

PDB Images (7)

Image of CATH 6fyz

6fyz

PDB 6fyz

Image of CATH 6fyzA

6fyzA

PDB Chain 6fyzA

Image of CATH 6fyzB

6fyzB

PDB Chain 6fyzB

Image of CATH 6fyzC

6fyzC

PDB Chain 6fyzC

Image of CATH 6fyzA00

6fyzA00

CATH Domain 6fyzA00

Image of CATH 6fyzB00

6fyzB00

CATH Domain 6fyzB00

Image of CATH 6fyzC00

6fyzC00

CATH Domain 6fyzC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6fyzA00	28 Feb, 2019	3.40.800.20	Assigned
6fyzB00	28 Feb, 2019	3.40.800.20	Assigned
6fyzC00	28 Feb, 2019	3.40.800.20	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56524	HDAC4_HUMAN	Homo sapiens	Histone deacetylase 4
P56524	HDAC4_HUMAN	Homo sapiens	Histone deacetylase 4
P56524	HDAC4_HUMAN	Homo sapiens	Histone deacetylase 4