PDB Information

PDB6FUG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.
Vulpetti, A., Ostermann, N., Randl, S., Yoon, T., Mac Sweeney, A., Cumin, F., Lorthiois, E., Rudisser, S., Erbel, P., Maibaum, J.
ACS Med Chem Lett
HeaderHydrolase
Released2018-02-27
Resolution2.210
CATH Insert Date06 Jul, 2018

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Chopped
D 06 Jul, 2018 Chopped
E 06 Jul, 2018 Chopped
F 06 Jul, 2018 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6fugA01 19 Jul, 2018 2.40.10.10 Assigned
6fugA02 19 Jul, 2018 2.40.10.10 Assigned
6fugB01 19 Jul, 2018 2.40.10.10 Assigned
6fugB02 19 Jul, 2018 2.40.10.10 Assigned
6fugC01 19 Jul, 2018 2.40.10.10 Assigned
6fugC02 19 Jul, 2018 2.40.10.10 Assigned
6fugD01 19 Jul, 2018 2.40.10.10 Assigned
6fugD02 19 Jul, 2018 2.40.10.10 Assigned
6fugE01 19 Jul, 2018 2.40.10.10 Assigned
6fugE02 19 Jul, 2018 2.40.10.10 Assigned
6fugF01 19 Jul, 2018 2.40.10.10 Assigned
6fugF02 19 Jul, 2018 2.40.10.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D