PDB Information

PDB6FS1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Tron, A.E., Belmonte, M.A., Adam, A., Aquila, B.M., Boise, L.H., Chiarparin, E., Cidado, J., Embrey, K.J., Gangl, E., Gibbons, F.D., Gregory, G.P., Hargreaves, D., Hendricks, J.A., Johannes, J.W., Johnstone, R.W., Kazmirski, S.L., Kettle, J.G., Lamb, M.L., Matulis, S.M., Nooka, A.K., Packer, M.J., Peng, B., Rawlins, P.B., Robbins, D.W., Schuller, A.G., Su, N., Yang, W., Ye, Q., Zheng, X., Secrist, J.P., Clark, E.A., Wilson, D.M., Fawell, S.E., Hird, A.W.
Nat Commun
HeaderImmune System
Released2018-02-18
Resolution1.600
CATH Insert Date30 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Dec, 2018 Chopped
B 30 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6fs1A01 31 Dec, 2018 1.10.437.10 Assigned
6fs1B01 31 Dec, 2018 1.10.437.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1