PDB Information

PDB6FMJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Thioamide substitution to probe the hydroxyproline recognition of VHL ligands.
Soares, P., Lucas, X., Ciulli, A.
Bioorg. Med. Chem.
HeaderLigase
Released2018-01-31
Resolution2.450
CATH Insert Date03 Jun, 2018

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped
E 03 Jun, 2018 Chopped
F 03 Jun, 2018 Chopped
G 03 Jun, 2018 Chopped
H 03 Jun, 2018 Chopped
I 03 Jun, 2018 Chopped
J 03 Jun, 2018 Chopped
K 03 Jun, 2018 Chopped
L 03 Jun, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6fmjA00 29 Jun, 2018 3.10.20.90 Assigned
6fmjB00 29 Jun, 2018 3.30.710.10 Assigned
6fmjC01 29 Jun, 2018 2.60.40.780 Assigned
6fmjC02 29 Jun, 2018 1.10.750.10 Assigned
6fmjD00 29 Jun, 2018 3.10.20.90 Assigned
6fmjE00 29 Jun, 2018 3.30.710.10 Assigned
6fmjF01 29 Jun, 2018 2.60.40.780 Assigned
6fmjF02 29 Jun, 2018 1.10.750.10 Assigned
6fmjG00 29 Jun, 2018 3.10.20.90 Assigned
6fmjH00 29 Jun, 2018 3.30.710.10 Assigned
6fmjI01 29 Jun, 2018 2.60.40.780 Assigned
6fmjI02 29 Jun, 2018 1.10.750.10 Assigned
6fmjJ00 29 Jun, 2018 3.10.20.90 Assigned
6fmjK00 29 Jun, 2018 3.30.710.10 Assigned
6fmjL01 29 Jun, 2018 2.60.40.780 Assigned
6fmjL02 29 Jun, 2018 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor