PDB 6fmd

PDB Information

PDB6FMD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
Sainas, S., Pippione, A.C., Lupino, E., Giorgis, M., Circosta, P., Gaidano, V., Goyal, P., Bonanni, D., Rolando, B., Cignetti, A., Ducime, A., Andersson, M., Jarva, M., Friemann, R., Piccinini, M., Ramondetti, C., Buccinna, B., Al-Karadaghi, S., Boschi, D., Saglio, G., Lolli, M.L.
J. Med. Chem.
HeaderOxidoreductase
Released2018-01-30
Resolution1.580
CATH Insert Date16 Jul, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6fmdA00 19 Jul, 2018 3.20.20.70 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02127 PYRD_HUMAN Homo sapiens Dihydroorotate dehydrogenase (quinone), mitochondrial
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