PDB Information

PDB6FGY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors.
Veenstra, S.J., Rueeger, H., Voegtle, M., Lueoend, R., Holzer, P., Hurth, K., Tintelnot-Blomley, M., Frederiksen, M., Rondeau, J.M., Jacobson, L., Staufenbiel, M., Neumann, U., Machauer, R.
Bioorg. Med. Chem. Lett.
HeaderHydrolase
Released2018-01-11
Resolution1.540
CATH Insert Date06 Jul, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6fgyA01 19 Jul, 2018 2.40.70.10 Assigned
6fgyA02 19 Jul, 2018 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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