PDB Information

PDB6F3E
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4.
Degorce, S.L., Anjum, R., Dillman, K.S., Drew, L., Groombridge, S.D., Halsall, C.T., Lenz, E.M., Lindsay, N.A., Mayo, M.F., Pink, J.H., Robb, G.R., Scott, J.S., Stokes, S., Xue, Y.
Bioorg. Med. Chem.
HeaderSignaling Protein
Released2017-11-28
Resolution2.670
CATH Insert Date03 Jun, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6f3eA01 12 Jul, 2018 3.30.200.20 Assigned
6f3eA02 12 Jul, 2018 1.10.510.10 Assigned
6f3eB01 12 Jul, 2018 3.30.200.20 Assigned
6f3eB02 12 Jul, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
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