PDB Information

PDB6F1X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.
Rahm, F., Viklund, J., Tresaugues, L., Ellermann, M., Giese, A., Ericsson, U., Forsblom, R., Ginman, T., Gunther, J., Hallberg, K., Lindstrom, J., Persson, L.B., Silvander, C., Talagas, A., Diaz-Saez, L., Fedorov, O., Huber, K.V.M., Panagakou, I., Siejka, P., Gorjanacz, M., Bauser, M., Andersson, M.
J. Med. Chem.
HeaderHydrolase
Released2017-11-23
Resolution1.900
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Holding pen
B 03 Jun, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P36639 8ODP_HUMAN Homo sapiens 7,8-dihydro-8-oxoguanine triphosphatase
P36639 8ODP_HUMAN Homo sapiens 7,8-dihydro-8-oxoguanine triphosphatase
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