PDB 6edb
PDB Information
| PDB | 6EDB |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA
|
| Header | Transferase/Dna |
| Released | 2018-08-09 |
| Resolution | 3.210 |
| CATH Insert Date | 02 Jun, 2019 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 02 Jun, 2019 | Chopped |
| B | 02 Jun, 2019 | Chopped |
| C | 02 Jun, 2019 | Rejected |
| D | 02 Jun, 2019 | Rejected |
CATH Domains (3)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6edbA01 | 03 Jun, 2019 | 1.10.1410.40 | Assigned |
| 6edbA02 | 03 Jun, 2019 | 3.30.460.90 | Assigned |
| 6edbB00 | 03 Jun, 2019 | 1.10.30.10 | Assigned |
UniProtKB Entries (3)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q8N884 | CGAS_HUMAN | Homo sapiens | Cyclic GMP-AMP synthase |
| Q8N884 | CGAS_HUMAN | Homo sapiens | Cyclic GMP-AMP synthase |
| Q05066 | SRY_HUMAN | Homo sapiens | Sex-determining region Y protein |
