PDB 6dwk

PDB Links
Overview

PDB Information

PDB	6DWK
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Knecht, K.M., Buzovetsky, O., Schneider, C., Thomas, D., Srikanth, V., Kaderali, L., Tofoleanu, F., Reiss, K., Ferreiros, N., Geisslinger, G., Batista, V.S., Ji, X., Cinatl Jr., J., Keppler, O.T., Xiong, Y. Proc. Natl. Acad. Sci. U.S.A.
Header	Hydrolase/Hydrolase Inhibitor
Released	2018-06-26
Resolution	2.300
CATH Insert Date	16 Dec, 2018

PDB Images (5)

Image of CATH 6dwk

6dwk

PDB 6dwk

Image of CATH 6dwkA

6dwkA

PDB Chain 6dwkA

Image of CATH 6dwkB

6dwkB

PDB Chain 6dwkB

Image of CATH 6dwkC

6dwkC

PDB Chain 6dwkC

Image of CATH 6dwkD

6dwkD

PDB Chain 6dwkD

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Holding pen
B	16 Dec, 2018	Holding pen
C	16 Dec, 2018	Holding pen
D	16 Dec, 2018	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1