PDB 6dwd

PDB Information

PDB6DWD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.
Knecht, K.M., Buzovetsky, O., Schneider, C., Thomas, D., Srikanth, V., Kaderali, L., Tofoleanu, F., Reiss, K., Ferreiros, N., Geisslinger, G., Batista, V.S., Ji, X., Cinatl Jr., J., Keppler, O.T., Xiong, Y.
Proc. Natl. Acad. Sci. U.S.A.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-06-26
Resolution1.700
CATH Insert Date16 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Holding pen
B 16 Dec, 2018 Holding pen
C 16 Dec, 2018 Holding pen
D 16 Dec, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9Y3Z3 SAMH1_HUMAN Homo sapiens Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3 SAMH1_HUMAN Homo sapiens Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3 SAMH1_HUMAN Homo sapiens Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3 SAMH1_HUMAN Homo sapiens Deoxynucleoside triphosphate triphosphohydrolase SAMHD1