PDB 6dw4

PDB Links
Overview

PDB Information

PDB	6DW4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Knecht, K.M., Buzovetsky, O., Schneider, C., Thomas, D., Srikanth, V., Kaderali, L., Tofoleanu, F., Reiss, K., Ferreiros, N., Geisslinger, G., Batista, V.S., Ji, X., Cinatl Jr., J., Keppler, O.T., Xiong, Y. Proc. Natl. Acad. Sci. U.S.A.
Header	Hydrolase/Hydrolase Inhibitor
Released	2018-06-26
Resolution	1.990
CATH Insert Date	16 Dec, 2018

PDB Images (5)

Image of CATH 6dw4

6dw4

PDB 6dw4

Image of CATH 6dw4A

6dw4A

PDB Chain 6dw4A

Image of CATH 6dw4B

6dw4B

PDB Chain 6dw4B

Image of CATH 6dw4C

6dw4C

PDB Chain 6dw4C

Image of CATH 6dw4D

6dw4D

PDB Chain 6dw4D

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Holding pen
B	16 Dec, 2018	Holding pen
C	16 Dec, 2018	Holding pen
D	16 Dec, 2018	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Q9Y3Z3	SAMH1_HUMAN	Homo sapiens	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1