PDB 6di1

PDB Information

PDB6DI1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene Source Homo sapiens
Primary Citation
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.
Caldwell, R., Liu-Bujalski, L., Qiu, H., Mochalkin, I., Jones, R., Neagu, C., Goutopoulos, A., Grenningloh, R., Johnson, T., Sherer, B., Gardberg, A., Follis, A.V., Morandi, F., Head, J.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2018-05-22
Resolution1.100
CATH Insert Date16 Dec, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6di1A01 28 Feb, 2019 3.30.200.20 Assigned
6di1A02 28 Feb, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
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