PDB 6d5g

PDB Links
Overview

PDB Information

PDB	6D5G
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. Hodges, T.R., Abbott, J.R., Little, A.J., Sarkar, D., Salovich, J.M., Howes, J.E., Akan, D.T., Sai, J., Arnold, A.L., Browning, C., Burns, M.C., Sobolik, T., Sun, Q., Beesetty, Y., Coker, J.A., Scharn, D., Stadtmueller, H., Rossanese, O.W., Phan, J., Waterson, A.G., McConnell, D.B., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2018-04-19
Resolution	1.920
CATH Insert Date	23 Sep, 2018

PDB Images (8)

Image of CATH 6d5g

6d5g

PDB 6d5g

Image of CATH 6d5gA

6d5gA

PDB Chain 6d5gA

Image of CATH 6d5gB

6d5gB

PDB Chain 6d5gB

Image of CATH 6d5gC

6d5gC

PDB Chain 6d5gC

Image of CATH 6d5gA00

6d5gA00

CATH Domain 6d5gA00

Image of CATH 6d5gB01

6d5gB01

CATH Domain 6d5gB01

Image of CATH 6d5gB02

6d5gB02

CATH Domain 6d5gB02

Image of CATH 6d5gC00

6d5gC00

CATH Domain 6d5gC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	23 Sep, 2018	Chopped
B	23 Sep, 2018	Chopped
C	23 Sep, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6d5gA00	24 Sep, 2018	3.40.50.300	Assigned
6d5gB01	24 Sep, 2018	1.20.870.10	Assigned
6d5gB02	24 Sep, 2018	1.10.840.10	Assigned
6d5gC00	24 Sep, 2018	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1