PDB 6cuo

PDB Links
Overview

PDB Information

PDB	6CUO
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. Abbott, J.R., Patel, P.A., Howes, J.E., Akan, D.T., Kennedy, J.P., Burns, M.C., Browning, C.F., Sun, Q., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. ACS Med Chem Lett
Header	Signaling Protein
Released	2018-03-26
Resolution	1.730
CATH Insert Date	10 Feb, 2019

PDB Images (8)

Image of CATH 6cuo

6cuo

PDB 6cuo

Image of CATH 6cuoA

6cuoA

PDB Chain 6cuoA

Image of CATH 6cuoB

6cuoB

PDB Chain 6cuoB

Image of CATH 6cuoC

6cuoC

PDB Chain 6cuoC

Image of CATH 6cuoA00

6cuoA00

CATH Domain 6cuoA00

Image of CATH 6cuoB01

6cuoB01

CATH Domain 6cuoB01

Image of CATH 6cuoB02

6cuoB02

CATH Domain 6cuoB02

Image of CATH 6cuoC00

6cuoC00

CATH Domain 6cuoC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	10 Feb, 2019	Chopped
B	10 Feb, 2019	Chopped
C	10 Feb, 2019	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6cuoA00	11 Feb, 2019	3.40.50.300	Assigned
6cuoB01	11 Feb, 2019	1.20.870.10	Assigned
6cuoB02	11 Feb, 2019	1.10.840.10	Assigned
6cuoC00	11 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1