PDB Information

PDB6CQ5
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK epsilon for the treatment of obesity.
Beyett, T.S., Gan, X., Reilly, S.M., Gomez, A.V., Chang, L., Tesmer, J.J.G., Saltiel, A.R., Showalter, H.D.
Bioorg. Med. Chem.
HeaderTransferase
Released2018-03-14
Resolution3.350
CATH Insert Date16 Dec, 2018

PDB Images (6)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6cq5A01 28 Feb, 2019 3.30.200.20 Assigned
6cq5A02 28 Feb, 2019 1.10.510.10 Assigned
6cq5A03 28 Feb, 2019 3.10.20.90 Assigned
6cq5A04 28 Feb, 2019 1.20.1270.420 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UHD2 TBK1_HUMAN Homo sapiens Serine/threonine-protein kinase TBK1
CATH-Gene3D is a Global Biodata Core Resource Learn more...