PDB Information

PDB6CFO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the alpha V138M variant of human pyruvate dehydrogenase.
Whitley, M.J., Arjunan, P., Nemeria, N.S., Korotchkina, L.G., Park, Y.H., Patel, M.S., Jordan, F., Furey, W.
J. Biol. Chem.
HeaderOxidoreductase
Released2018-02-15
Resolution2.700
CATH Insert Date16 Jul, 2018

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6cfoA00 19 Jul, 2018 3.40.50.970 Assigned
6cfoB01 19 Jul, 2018 3.40.50.970 Assigned
6cfoB02 19 Jul, 2018 3.40.50.920 Assigned
6cfoC00 19 Jul, 2018 3.40.50.970 Assigned
6cfoD01 19 Jul, 2018 3.40.50.970 Assigned
6cfoD02 19 Jul, 2018 3.40.50.920 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
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