PDB Information

PDB6CER
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the alpha V138M variant of human pyruvate dehydrogenase.
Whitley, M.J., Arjunan, P., Nemeria, N.S., Korotchkina, L.G., Park, Y.H., Patel, M.S., Jordan, F., Furey, W.
J. Biol. Chem.
HeaderOxidoreductase
Released2018-02-12
Resolution2.690
CATH Insert Date16 Jul, 2018

PDB Images (21)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped
E 16 Jul, 2018 Chopped
F 16 Jul, 2018 Chopped
G 16 Jul, 2018 Chopped
H 16 Jul, 2018 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6cerA00 19 Jul, 2018 3.40.50.970 Assigned
6cerB01 19 Jul, 2018 3.40.50.970 Assigned
6cerB02 19 Jul, 2018 3.40.50.920 Assigned
6cerC00 19 Jul, 2018 3.40.50.970 Assigned
6cerD01 19 Jul, 2018 3.40.50.970 Assigned
6cerD02 19 Jul, 2018 3.40.50.920 Assigned
6cerE00 19 Jul, 2018 3.40.50.970 Assigned
6cerF01 19 Jul, 2018 3.40.50.970 Assigned
6cerF02 19 Jul, 2018 3.40.50.920 Assigned
6cerG00 19 Jul, 2018 3.40.50.970 Assigned
6cerH01 19 Jul, 2018 3.40.50.970 Assigned
6cerH02 19 Jul, 2018 3.40.50.920 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
P08559 ODPA_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
P11177 ODPB_HUMAN Homo sapiens Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
CATH-Gene3D is a Global Biodata Core Resource Learn more...