PDB 6ccy

PDB Information

PDB6CCY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT.
Parthasarathy, S., Henry, K., Pei, H., Clayton, J., Rempala, M., Johns, D., De Frutos, O., Garcia, P., Mateos, C., Pleite, S., Wang, Y., Stout, S., Condon, B., Ashok, S., Lu, Z., Ehlhardt, W., Raub, T., Lai, M., Geeganage, S., Burkholder, T.P.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Inhibitor
Released2018-02-07
Resolution2.180
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ccyA01 12 Jul, 2018 3.30.200.20 Assigned
6ccyA02 12 Jul, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P31749 AKT1_HUMAN Homo sapiens RAC-alpha serine/threonine-protein kinase
Q16513 PKN2_HUMAN Homo sapiens Serine/threonine-protein kinase N2
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