PDB 6c42

PDB Information

PDB6C42
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
Fanning, S.W., Hodges-Gallagher, L., Myles, D.C., Sun, R., Fowler, C.E., Plant, I.N., Green, B.D., Harmon, C.L., Greene, G.L., Kushner, P.J.
Nat Commun
HeaderTrascription/Transcription Inhibitor
Released2018-01-11
Resolution2.000
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6c42A00 28 Jun, 2018 1.10.565.10 Assigned
6c42B00 28 Jun, 2018 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
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