PDB 6bx8

PDB Information

PDB6BX8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
Cohen, I., Coban, M., Shahar, A., Sankaran, B., Hockla, A., Lacham, S., Caulfield, T.R., Radisky, E.S., Papo, N.
J. Biol. Chem.
HeaderHydrolase
Released2017-12-18
Resolution1.980
CATH Insert Date10 Feb, 2019

PDB Images (21)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 10 Feb, 2019 Chopped
B 10 Feb, 2019 Chopped
C 10 Feb, 2019 Chopped
D 10 Feb, 2019 Chopped
E 10 Feb, 2019 Chopped
F 10 Feb, 2019 Chopped
G 10 Feb, 2019 Chopped
H 10 Feb, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6bx8A01 11 Feb, 2019 Holding pen
6bx8A02 11 Feb, 2019 2.40.10.10 Assigned
6bx8B00 11 Feb, 2019 4.10.410.10 Assigned
6bx8C01 11 Feb, 2019 Holding pen
6bx8C02 11 Feb, 2019 2.40.10.10 Assigned
6bx8D00 11 Feb, 2019 4.10.410.10 Assigned
6bx8E01 11 Feb, 2019 Holding pen
6bx8E02 11 Feb, 2019 2.40.10.10 Assigned
6bx8F00 11 Feb, 2019 4.10.410.10 Assigned
6bx8G01 11 Feb, 2019 Holding pen
6bx8G02 11 Feb, 2019 2.40.10.10 Assigned
6bx8H00 11 Feb, 2019 4.10.410.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P10646 TFPI1_HUMAN Homo sapiens Tissue factor pathway inhibitor
P10646 TFPI1_HUMAN Homo sapiens Tissue factor pathway inhibitor
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P10646 TFPI1_HUMAN Homo sapiens Tissue factor pathway inhibitor
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P10646 TFPI1_HUMAN Homo sapiens Tissue factor pathway inhibitor