PDB 6bw2

PDB Links
Overview

PDB Information

PDB	6BW2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design. Shaw, S., Bian, Z., Zhao, B., Tarr, J.C., Veerasamy, N., Jeon, K.O., Belmar, J., Arnold, A.L., Fogarty, S.A., Perry, E., Sensintaffar, J.L., Camper, D.V., Rossanese, O.W., Lee, T., Olejniczak, E.T., Fesik, S.W. J. Med. Chem.
Header	Apoptosis
Released	2017-12-14
Resolution	2.750
CATH Insert Date	03 Jun, 2018

PDB Images (9)

Image of CATH 6bw2

6bw2

PDB 6bw2

Image of CATH 6bw2A

6bw2A

PDB Chain 6bw2A

Image of CATH 6bw2B

6bw2B

PDB Chain 6bw2B

Image of CATH 6bw2C

6bw2C

PDB Chain 6bw2C

Image of CATH 6bw2D

6bw2D

PDB Chain 6bw2D

Image of CATH 6bw2A01

6bw2A01

CATH Domain 6bw2A01

Image of CATH 6bw2B01

6bw2B01

CATH Domain 6bw2B01

Image of CATH 6bw2C01

6bw2C01

CATH Domain 6bw2C01

Image of CATH 6bw2D01

6bw2D01

CATH Domain 6bw2D01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped
B	03 Jun, 2018	Chopped
C	03 Jun, 2018	Chopped
D	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bw2A01	28 Jun, 2018	1.10.437.10	Assigned
6bw2B01	28 Jun, 2018	1.10.437.10	Assigned
6bw2C01	28 Jun, 2018	1.10.437.10	Assigned
6bw2D01	28 Jun, 2018	1.10.437.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1