PDB 6bvl

PDB Links
Overview

PDB Information

PDB	6BVL
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. Abbott, J.R., Hodges, T.R., Daniels, R.N., Patel, P.A., Kennedy, J.P., Howes, J.E., Akan, D.T., Burns, M.C., Sai, J., Sobolik, T., Beesetty, Y., Lee, T., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2017-12-13
Resolution	1.750
CATH Insert Date	16 Dec, 2018

PDB Images (8)

Image of CATH 6bvl

6bvl

PDB 6bvl

Image of CATH 6bvlA

6bvlA

PDB Chain 6bvlA

Image of CATH 6bvlB

6bvlB

PDB Chain 6bvlB

Image of CATH 6bvlC

6bvlC

PDB Chain 6bvlC

Image of CATH 6bvlA00

6bvlA00

CATH Domain 6bvlA00

Image of CATH 6bvlB01

6bvlB01

CATH Domain 6bvlB01

Image of CATH 6bvlB02

6bvlB02

CATH Domain 6bvlB02

Image of CATH 6bvlC00

6bvlC00

CATH Domain 6bvlC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bvlA00	28 Feb, 2019	3.40.50.300	Assigned
6bvlB01	28 Feb, 2019	1.20.870.10	Assigned
6bvlB02	28 Feb, 2019	1.10.840.10	Assigned
6bvlC00	28 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas