PDB 6bvk

PDB Links
Overview

PDB Information

PDB	6BVK
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. Abbott, J.R., Hodges, T.R., Daniels, R.N., Patel, P.A., Kennedy, J.P., Howes, J.E., Akan, D.T., Burns, M.C., Sai, J., Sobolik, T., Beesetty, Y., Lee, T., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2017-12-13
Resolution	1.800
CATH Insert Date	16 Dec, 2018

PDB Images (8)

Image of CATH 6bvk

6bvk

PDB 6bvk

Image of CATH 6bvkA

6bvkA

PDB Chain 6bvkA

Image of CATH 6bvkB

6bvkB

PDB Chain 6bvkB

Image of CATH 6bvkC

6bvkC

PDB Chain 6bvkC

Image of CATH 6bvkA00

6bvkA00

CATH Domain 6bvkA00

Image of CATH 6bvkB01

6bvkB01

CATH Domain 6bvkB01

Image of CATH 6bvkB02

6bvkB02

CATH Domain 6bvkB02

Image of CATH 6bvkC00

6bvkC00

CATH Domain 6bvkC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bvkA00	28 Feb, 2019	3.40.50.300	Assigned
6bvkB01	28 Feb, 2019	1.20.870.10	Assigned
6bvkB02	28 Feb, 2019	1.10.840.10	Assigned
6bvkC00	28 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas