PDB 6bvi

PDB Links
Overview

PDB Information

PDB	6BVI
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. Abbott, J.R., Hodges, T.R., Daniels, R.N., Patel, P.A., Kennedy, J.P., Howes, J.E., Akan, D.T., Burns, M.C., Sai, J., Sobolik, T., Beesetty, Y., Lee, T., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2017-12-13
Resolution	1.750
CATH Insert Date	16 Dec, 2018

PDB Images (8)

Image of CATH 6bvi

6bvi

PDB 6bvi

Image of CATH 6bviA

6bviA

PDB Chain 6bviA

Image of CATH 6bviB

6bviB

PDB Chain 6bviB

Image of CATH 6bviC

6bviC

PDB Chain 6bviC

Image of CATH 6bviA00

6bviA00

CATH Domain 6bviA00

Image of CATH 6bviB01

6bviB01

CATH Domain 6bviB01

Image of CATH 6bviB02

6bviB02

CATH Domain 6bviB02

Image of CATH 6bviC00

6bviC00

CATH Domain 6bviC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Chopped
B	16 Dec, 2018	Chopped
C	16 Dec, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bviA00	28 Feb, 2019	3.40.50.300	Assigned
6bviB01	28 Feb, 2019	1.20.870.10	Assigned
6bviB02	28 Feb, 2019	1.10.840.10	Assigned
6bviC00	28 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1