PDB 6bl2

PDB Links
Overview

PDB Information

PDB	6BL2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. Jakob, C.G., Upadhyay, A.K., Donner, P.L., Nicholl, E., Addo, S.N., Qiu, W., Ling, C., Gopalakrishnan, S.M., Torrent, M., Cepa, S.P., Shanley, J., Shoemaker, A.R., Sun, C.C., Vasudevan, A., Woller, K.R., Shotwell, J.B., Shaw, B., Bian, Z., Hutti, J.E. J. Med. Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2017-11-09
Resolution	1.920
CATH Insert Date	29 Jul, 2018

PDB Images (7)

Image of CATH 6bl2

6bl2

PDB 6bl2

Image of CATH 6bl2A

6bl2A

PDB Chain 6bl2A

Image of CATH 6bl2B

6bl2B

PDB Chain 6bl2B

Image of CATH 6bl2C

6bl2C

PDB Chain 6bl2C

Image of CATH 6bl2A00

6bl2A00

CATH Domain 6bl2A00

Image of CATH 6bl2B00

6bl2B00

CATH Domain 6bl2B00

Image of CATH 6bl2C00

6bl2C00

CATH Domain 6bl2C00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jul, 2018	Chopped
B	29 Jul, 2018	Chopped
C	29 Jul, 2018	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bl2A00	30 Jul, 2018	3.40.718.10	Assigned
6bl2B00	30 Jul, 2018	3.40.718.10	Assigned
6bl2C00	30 Jul, 2018	3.40.718.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic