PDB 6bl1

PDB Links
Overview

PDB Information

PDB	6BL1
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. Jakob, C.G., Upadhyay, A.K., Donner, P.L., Nicholl, E., Addo, S.N., Qiu, W., Ling, C., Gopalakrishnan, S.M., Torrent, M., Cepa, S.P., Shanley, J., Shoemaker, A.R., Sun, C.C., Vasudevan, A., Woller, K.R., Shotwell, J.B., Shaw, B., Bian, Z., Hutti, J.E. J. Med. Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2017-11-09
Resolution	2.020
CATH Insert Date	29 Jul, 2018

PDB Images (7)

Image of CATH 6bl1

6bl1

PDB 6bl1

Image of CATH 6bl1A

6bl1A

PDB Chain 6bl1A

Image of CATH 6bl1B

6bl1B

PDB Chain 6bl1B

Image of CATH 6bl1C

6bl1C

PDB Chain 6bl1C

Image of CATH 6bl1A00

6bl1A00

CATH Domain 6bl1A00

Image of CATH 6bl1B00

6bl1B00

CATH Domain 6bl1B00

Image of CATH 6bl1C00

6bl1C00

CATH Domain 6bl1C00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jul, 2018	Chopped
B	29 Jul, 2018	Chopped
C	29 Jul, 2018	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6bl1A00	30 Jul, 2018	3.40.718.10	Assigned
6bl1B00	30 Jul, 2018	3.40.718.10	Assigned
6bl1C00	30 Jul, 2018	3.40.718.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic