PDB Information

PDB6BBA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Wong, K.S., Mabanglo, M.F., Seraphim, T.V., Mollica, A., Mao, Y.Q., Rizzolo, K., Leung, E., Moutaoufik, M.T., Hoell, L., Phanse, S., Goodreid, J., Barbosa, L.R.S., Ramos, C.H.I., Babu, M., Mennella, V., Batey, R.A., Schimmer, A.D., Houry, W.A.
Cell Chem Biol
HeaderHydrolase/Hydrolase Inhibitor
Released2017-10-17
Resolution2.800
CATH Insert Date16 Jul, 2018

PDB Images (22)

PDB Prints

PDB Chains (14)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped
E 16 Jul, 2018 Chopped
F 16 Jul, 2018 Chopped
G 16 Jul, 2018 Chopped
H 16 Jul, 2018 Rejected
I 16 Jul, 2018 Rejected
J 16 Jul, 2018 Rejected
K 16 Jul, 2018 Rejected
L 16 Jul, 2018 Rejected
M 16 Jul, 2018 Rejected
N 16 Jul, 2018 Rejected

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
6bbaA00 19 Jul, 2018 3.90.226.10 Assigned
6bbaB00 19 Jul, 2018 3.90.226.10 Assigned
6bbaC00 19 Jul, 2018 3.90.226.10 Assigned
6bbaD00 19 Jul, 2018 3.90.226.10 Assigned
6bbaE00 19 Jul, 2018 3.90.226.10 Assigned
6bbaF00 19 Jul, 2018 3.90.226.10 Assigned
6bbaG00 19 Jul, 2018 3.90.226.10 Assigned

UniProtKB Entries (7)

Accession Gene ID Taxon Description
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
Q16740 CLPP_HUMAN Homo sapiens ATP-dependent Clp protease proteolytic subunit, mitochondrial
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