PDB 6bax

PDB Information

PDB6BAX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase
Wei, B., Labadie, S.S., Robarge, K., Chen, J., Chen, Z., Corson, L.B., Ding, C.Z., DiPasquale, A.G., Dragovich, P.S., Eigenbrot, C., Evangelista, M., Fauber, B.P., Goa, Z., Ge, H., Hitz, A., Ho, Q., Lai, K.W., Liu, W., Liu, Y., Li, C., Ma, S., Malek, S., O'Brien, T., Pang, J., Peterson, D., Salphati, L., Sideris, S., Ultsch, M., Yen, I., Yue, Q., Zhang, H., Zhou, A., Purkey, H.E.
To Be Published
HeaderOxidoreductase/Inhibitor
Released2017-10-16
Resolution2.050
CATH Insert Date16 Dec, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6baxA01 28 Feb, 2019 3.40.50.720 Assigned
6baxA02 28 Feb, 2019 3.90.110.10 Assigned
6baxB01 28 Feb, 2019 3.40.50.720 Assigned
6baxB02 28 Feb, 2019 3.90.110.10 Assigned
6baxC01 28 Feb, 2019 3.40.50.720 Assigned
6baxC02 28 Feb, 2019 3.90.110.10 Assigned
6baxD01 28 Feb, 2019 3.40.50.720 Assigned
6baxD02 28 Feb, 2019 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
CATH-Gene3D is a Global Biodata Core Resource Learn more...