Synthesis and Pharmacological Characterization of C4beta-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3Receptor Agonist.
Monn, J.A., Henry, S.S., Massey, S.M., Clawson, D.K., Chen, Q., Diseroad, B.A., Bhardwaj, R.M., Atwell, S., Lu, F., Wang, J., Russell, M., Heinz, B.A., Wang, X.S., Carter, J.H., Getman, B.G., Adragni, K., Broad, L.M., Sanger, H.E., Ursu, D., Catlow, J.T., Swanson, S., Johnson, B.G., Shaw, D.B., McKinzie, D.L., Hao, J.
J. Med. Chem.
