The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.
Riggs, J.R., Nagy, M., Elsner, J., Erdman, P., Cashion, D., Robinson, D., Harris, R., Huang, D., Tehrani, L., Deyanat-Yazdi, G., Narla, R.K., Peng, X., Tran, T., Barnes, L., Miller, T., Katz, J., Tang, Y., Chen, M., Moghaddam, M.F., Bahmanyar, S., Pagarigan, B., Delker, S., LeBrun, L., Chamberlain, P.P., Calabrese, A., Canan, S.S., Leftheris, K., Zhu, D., Boylan, J.F.
J. Med. Chem.