PDB Information

PDB6AXF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Vercoulen, Y., Kondo, Y., Iwig, J.S., Janssen, A., White, K.A., Amini, M., Barber, D.L., Kuriyan, J., Roose, J.P.
Elife
HeaderProtein Binding
Released2017-09-06
Resolution3.100
CATH Insert Date14 Nov, 2017

PDB Images (25)

PDB Prints

PDB Chains (16)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Domchop review
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Holding pen
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Holding pen
F 14 Nov, 2017 Chopped
G 14 Nov, 2017 Holding pen
H 14 Nov, 2017 Chopped
I 14 Nov, 2017 Holding pen
J 14 Nov, 2017 Chopped
K 14 Nov, 2017 Holding pen
L 14 Nov, 2017 Chopped
M 14 Nov, 2017 Holding pen
N 14 Nov, 2017 Chopped
O 14 Nov, 2017 Holding pen
P 14 Nov, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6axfB00 10 Dec, 2017 3.40.50.300 Assigned
6axfD00 10 Dec, 2017 3.40.50.300 Assigned
6axfF00 10 Dec, 2017 3.40.50.300 Assigned
6axfH00 10 Dec, 2017 3.40.50.300 Assigned
6axfJ00 10 Dec, 2017 3.40.50.300 Assigned
6axfL00 10 Dec, 2017 3.40.50.300 Assigned
6axfN00 10 Dec, 2017 3.40.50.300 Assigned
6axfP00 10 Dec, 2017 3.40.50.300 Assigned

UniProtKB Entries (16)

Accession Gene ID Taxon Description
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
Q7LDG7 GRP2_HUMAN Homo sapiens RAS guanyl-releasing protein 2
P61224 RAP1B_HUMAN Homo sapiens Ras-related protein Rap-1b