PDB Information

PDB6AAH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Hamaguchi, H., Amano, Y., Moritomo, A., Shirakami, S., Nakajima, Y., Nakai, K., Nomura, N., Ito, M., Higashi, Y., Inoue, T.
Bioorg. Med. Chem.
HeaderTransferase/Inhibitor
Released2018-07-18
Resolution1.830
CATH Insert Date19 Aug, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2018 Chopped
B 19 Aug, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6aahA01 20 Aug, 2018 3.30.200.20 Assigned
6aahA02 20 Aug, 2018 1.10.510.10 Assigned
6aahB01 20 Aug, 2018 3.30.200.20 Assigned
6aahB02 20 Aug, 2018 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P23458 JAK1_HUMAN Homo sapiens Tyrosine-protein kinase JAK1
P23458 JAK1_HUMAN Homo sapiens Tyrosine-protein kinase JAK1
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