PDB Information

PDB5ZHI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Primary Citation
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong, W., Pasunooti, K.K., Balamkundu, S., Wong, Y.H., Nah, Q., Gadi, V., Gnanakalai, S., Chionh, Y.H., McBee, M.E., Gopal, P., Lim, S.H., Olivier, N., Buurman, E.T., Dick, T., Liu, C.F., Lescar, J., Dedon, P.C.
J.Med.Chem.
HeaderTransferase
Released2018-03-13
Resolution2.200
CATH Insert Date10 Mar, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Mar, 2019 Chopped
B 10 Mar, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5zhiA01 11 Mar, 2019 3.40.1280.10 Assigned
5zhiA02 11 Mar, 2019 1.10.1270.20 Assigned
5zhiB01 11 Mar, 2019 3.40.1280.10 Assigned
5zhiB02 11 Mar, 2019 1.10.1270.20 Assigned

UniProtKB Entries (0)

Accession Gene ID Taxon Description
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